I have only had leaf mutations. Once I had a strain that got bleach spots on the buds. I thought i may of been light, but no way, since it was a cheap LED, and it didnt even happen on the top buds. Come to find out it was from a Manganese definecy. then next round i grew the same exact strain that was a clone from the one before, and gave it the required amount of nutes, and it looked, and smelled like a different plant. Very sensitive.